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Peptides serve as effective drugs in the clinic today. However the inherent drawbacks of peptide structures can limit their efficacy as drugs. To overcome this researchers are developing new methods to create ‘tailor-made’ peptides and proteins with improved pharmacological properties.Design of Peptides and Proteins provides an overview of the experimental and computational methods for peptide and protein design, with an emphasis on specific applications for therapeutics and biomedical research. Topics covered include:- Computer modeling of peptides and proteins
- Peptidomimetics
- Design and synthesis of cyclic peptides
- Carbohydrates in peptide and protein design
- De novo design of peptides and proteins
- Medical development applications
- An extended case study – the design of insulin variants
Design of Peptides and Proteins presents the state-of-the-art of this exciting approach for therapeutics, with contributions from international experts. It is an essential resource for academic and industrial scientists in the fields of peptide and protein drug design, biomedicine, biochemistry, biophysics, molecular modelling, synthetic organic chemistry and medicinal pharmaceuticalchemistry.Auteur :Nathalie Van Laethem Edition:Dunod Pages:514 Format:pdf Language:FrenshDownload this ebook : Peptide and Protein Design
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Ce livre couvre l’ensemble de la fonction Marketing :Les Savoirs : notions de marketing stratégique,opérationnel, client, mix-marketing…Les Savoir-faire : réaliser une étude, un plan marketing,une veille efficace ; segmenter et cibler un marché ;piloter une innovation ; construire une communicationmulticanal ; préparer un budget…Les Savoir-être : comportements efficaces dans lesrelations interpersonnelles, pour faire face auxcomportements difficiles, pour convaincre, gérer sontemps, être créatif…Ses atouts sont :Un contenu actuel et exhaustif, issu de vingt ans depratique du marketing.Une circulation aisée dans l’ouvrage, grâce à une miseen page aérée et interactive : onglets, renvois, mise encouleur, encadrés…Un caractère fortement opérationnel, à travers desfiches action et de nombreux exercices d’application.Auteur :Nathalie Van Laethem Edition:Dunod Pages:514 Format:pdf Language:FrenshTélécharger ce livre électronique :Toute la Fonction Marketing
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Ce livre, conçu pour permettre le travail de l'étudiant en autonomie, présente les connaissances de base indispensables à la détermination des sections d'armatures des ouvrages élémentaires d'une structure porteuse tels que semelles, poteaux, poutres, planchers. Il traite également desméthodes de vérification des contraintes du béton et de l'acier dans une section fléchie. Il utilise des méthodes simples faisant appel au calcul classique et à l'utilisation des tableaux avec leur mode d'exploitation. Il suit les dernières réglementations en vigueur et précise les dispositions constructivesAuteur : Jacques L,Hemri Renaud Edition : Foucher Pages:135 Format: pdf Language:FrenshDownload this ebook : Béton Armé Guide de Calcul
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Are you interested in starting a blog but can’t decide on which service to use? Google’s Blogger offers many advantages over other blog publishing systems, including seamless integration with Google services and web applications.
Beginning Google Blogger is a complete resource on how to create and manage ablog using Blogger. The book offers step-by-step instructions and visual aids which walk you through both the basics of Blogger and the advanced features it offers from creating a new blog and choosing fonts and colors, and installing custom blog graphics; to converting from a 2-column to a 3-column layout, setting up a domain name and creating an online store with a built-in navigational bar.
The journey from newbie to experienced blogger will be fun and challenging. You’ll learn practical applications of the most popular gadgets, search engine optimization tips, how to make money using Blogger, and, overall, taking blogging to a new level by incorporating social networking tools, using advanced blog design techniques, setting up a custom domain and creating an online store.Auteur : Heather Wright-Porto Edition : Apress Pages:194 Format: pdf Language:English
