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Peptides serve as effective drugs in
the clinic today. However the inherent drawbacks of peptide structures can
limit their efficacy as drugs. To overcome this researchers are developing new
methods to create ‘tailor-made’ peptides and proteins with improved pharmacological properties.
Design of Peptides and Proteins
provides an overview of the experimental and computational methods for peptide
and protein design, with an emphasis on specific applications for therapeutics
and biomedical research. Topics covered include:
- Computer modeling of peptides and proteins
- Peptidomimetics
- Design and synthesis of cyclic peptides
- Carbohydrates in peptide and protein design
- De novo design of peptides and proteins
- Medical development applications
- An extended case study – the design of insulin variants
Design of Peptides and Proteins
presents the state-of-the-art of this exciting approach for therapeutics, with
contributions from international experts. It is an essential resource for
academic and industrial scientists in the fields of peptide and protein drug
design, biomedicine, biochemistry, biophysics, molecular modelling, synthetic
organic chemistry and medicinal pharmaceuticalchemistry.
Auteur :Nathalie
Van Laethem Edition:Dunod Pages:514 Format:pdf Language:Frensh
Download this ebook : Peptide and Protein Design
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